NAD+

Description

NAD⁺ (Nicotinamide Adenine Dinucleotide)

Overview: NAD⁺ is a vital coenzyme found in every living cell. While not a peptide, it is often included in “peptide therapy” discussions because of its frequent co-administration with peptides. NAD⁺ is essential for energy production, cellular repair, and overall metabolic function.

Core Biological Roles

• Energy Metabolism: Central to converting carbohydrates, fats, and proteins into ATP via glycolysis, the Krebs cycle, and oxidative phosphorylation.
• DNA Repair: Serves as a cofactor for PARPs (poly ADP-ribose polymerases), enzymes critical for repairing DNA damage.
• Gene Expression & Longevity: Activates sirtuins, proteins that regulate inflammation, metabolism, and cellular aging pathways.
• Cell Signaling: Involved in calcium signaling and intracellular communication.
• Neuroprotection: Supports brain cell survival, resilience, and cognitive performance.

Why NAD⁺ Declines with Age

Cellular NAD⁺ levels naturally decrease over time, contributing to reduced energy, slower repair processes, and impaired stress response as we age.

Potential Benefits of NAD⁺ Supplementation

• Increase energy levels and reduce fatigue.
• Improve mental clarity, focus, and memory.
• Enhance mitochondrial efficiency and function.
• Support DNA repair and longevity pathways.
• Reduce systemic inflammation.
• Aid recovery from neurological stress or injury.

Clinical Research Highlights

• Anti-aging: Animal studies suggest extended lifespan with enhanced NAD⁺ availability.
• Neurodegeneration: Preclinical studies show potential protective effects against Alzheimer’s, Parkinson’s, and other conditions.
• Metabolic Health: Research indicates possible improvements in insulin sensitivity and lipid profiles.

Bottom Line

NAD⁺ is a universal cellular coenzyme essential for energy, repair, and longevity pathways. Its age-related decline has made it a central focus of research into metabolism, aging, and neuroprotection.

Research Use Only: NAD⁺ is supplied strictly for laboratory and research purposes. It is not approved for human consumption, medical, or veterinary use.

Product Specifications

• Quantity: 500 mg or 1,000 mg vial
• Form: Lyophilized powder
• Purity: ≥99% (HPLC)
• Molecular Weight: 663.40 Da
• Solubility: Soluble in sterile water or compatible aqueous buffers
• Characterization: HPLC, Mass Spectrometry
• CAS Number: 53-84-9

Storage and Handling

Store at −20 °C (−4 °F) or below. Store in the original vial, sealed and protected from light and moisture until use. Avoid repeated freeze-thaw cycles.

Disclaimer, Intended Use & Terms of Sale

All content and information provided are for educational and research reference purposes only. This product and its associated data have not been evaluated by the U.S. Food and Drug Administration, and no claims are made regarding the diagnosis, treatment, cure, or prevention of any disease. No representations or warranties are made regarding safety, effectiveness, or outcomes.

This product is intended strictly for in vitro laboratory research use only and is not for clinical use. It is not approved for human or animal administration and must not be used in food, dietary supplements, pharmaceuticals, cosmetics, or any consumer applications.

By purchasing from Alpha One Nutrition, the buyer affirms that they are a qualified researcher or institution with the appropriate training and facilities to handle research compounds in compliance with all applicable laws and regulations. All sales are final.