Description
TB-500 (Thymosin Beta-4 Fragment)
Overview: TB-500 is a synthetic peptide fragment of Thymosin Beta-4, a naturally occurring protein found in nearly all human and animal cells. It has been widely studied in preclinical research for its role in tissue repair, cell migration, and wound healing. TB-500 is often investigated alone or alongside BPC-157 as part of the so-called “Wolverine Stack.”
Mechanism & Preclinical Evidence
- Cell Migration: Enhances keratinocyte and endothelial cell migration to sites of tissue injury.
- Angiogenesis: Promotes new blood vessel growth, supporting nutrient and oxygen delivery to healing tissue.
- Tissue Remodeling: Regulates actin, a protein critical for cell structure and movement, facilitating repair and regeneration.
- Anti-Inflammatory: Reduces inflammatory signaling in injury models, aiding recovery.
Reported Research Applications
- Muscle, tendon, and ligament injury recovery.
- Wound healing and scar tissue reduction.
- Joint repair and improved mobility.
- Synergistic effects with BPC-157 in tissue regeneration research.
Bottom Line
TB-500 is a synthetic fragment of Thymosin Beta-4 studied for its regenerative properties. Its roles in angiogenesis, cell migration, and tissue remodeling have made it a key focus of laboratory research, often in combination with BPC-157.
Research Use Only: TB-500 is provided strictly for laboratory and research purposes. It is not approved for human consumption, medical, or veterinary use.




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