IPAMORELIN

Description

Ipamorelin

Overview: Ipamorelin is a synthetic growth-hormone-releasing peptide (GHRP). It is a small pentapeptide (Aib-His-D-2-Nal-D-Phe-Lys-NH₂) that acts as a selective agonist of the ghrelin/growth-hormone secretagogue receptor (GHS-R1a). By binding this receptor, it stimulates the pituitary to release endogenous growth hormone (GH). Originally developed by Novo Nordisk, Ipamorelin has since been studied in multiple clinical research settings.

Mechanism & What Makes It Different

Ipamorelin stimulates GH secretion through GHS-R activation but is distinct in its selectivity. Earlier GHRPs often elevated other pituitary hormones such as ACTH/cortisol, prolactin, LH/FSH, or TSH. Ipamorelin, by contrast, has been shown in most studies to increase GH release without significantly affecting those other pathways. This selective profile makes it a “cleaner” GH secretagogue for research purposes.

Pharmacology & Dosing (What Trials Show)

Pharmacokinetic and pharmacodynamic data in humans show:

• Onset & half-life: Short plasma half-life of ~1–2 hours after administration.
• Dosing effects: Dose-dependent GH peaks observed after subcutaneous or intravenous dosing.
• Pulse pattern: Because of its short duration, Ipamorelin produces discrete GH pulses rather than prolonged exposure.

Bottom Line

Ipamorelin is a potent and selective GH secretagogue. Its unique profile—stimulating GH release without markedly affecting other hormones—has made it an attractive candidate for research into growth hormone regulation.

Product Specifications

• Quantity: 5 mg or 10 mg vial
• Form: Lyophilized powder
• Purity: ≥99% (HPLC)
• Solubility: Soluble in sterile water or compatible aqueous buffers
• Characterization: HPLC, Mass Spectrometry
• CAS Number: 170851-70-4

Storage and Handling

Store at −20 °C (−4 °F) or below. Store in the original vial, sealed and protected from light and moisture until use. Avoid repeated freeze-thaw cycles.

Research Use Only: Ipamorelin is provided strictly for laboratory and research purposes. It is not approved for human consumption, medical, or veterinary use.

Disclaimer, Intended Use & Terms of Sale

All content and information provided are for educational and research reference purposes only. This product and its associated data have not been evaluated by the U.S. Food and Drug Administration, and no claims are made regarding the diagnosis, treatment, cure, or prevention of any disease. No representations or warranties are made regarding safety, effectiveness, or outcomes.

This product is intended strictly for in vitro laboratory research use only and is not for clinical use. It is not approved for human or animal administration and must not be used in food, dietary supplements, pharmaceuticals, cosmetics, or any consumer applications.

By purchasing from Alpha One Nutrition, the buyer affirms that they are a qualified researcher or institution with the appropriate training and facilities to handle research compounds in compliance with all applicable laws and regulations. All sales are final.